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Client Survey Cape Town

VZV

VZV IgG
VZV IgM

Varicella (chicken pox) is an acute, highly contagious viral disease with worldwide distribution, seasonal prevalence in winter and spring, characterized by generalized vesicular exanthema often accompanied by fever. While mostly a mild disorder in childhood, varicella tends to be more severe in adults and it may be fatal, especially in neonates and in immunocompromised subjects. Varicella-zoster virus (VZV), a Herpesviridae, is the causative agent of the disease that shows little genetic variation (only one serotype is known). Following primary infection, the virus remains latent in neural ganglia, and upon subsequent reactivation VZV may cause zoster (shingles), a disease mainly affecting the elderly and immunocompromised persons, that consists in painful, circumscribed eruption of vesicular lesions with inflammation of associated dorsal root or cranial nerve sensory ganglia. Evaluation of specific immune status for VZV may guide management of immunosuppressed patients and administration of antiviral agents. Varicella infection occurring in susceptible pregnant women can lead to severe, and even fatal, disease. Infection occurring in the first four months of pregnancy can lead to child deformity, while infection at the time of delivery may cause life-threatening infection in newborns. Although individual cases may be prevented or modified by VZV immunoglobulin administration or treated with antiviral drugs, varicella can be controlled only by vaccination.

DiaSorin Liaison VZV IgG

2-step immunoluminometric sandwich assay using directly coated magnetic microparticles
Sample matrix: Serum, Plasma
Sample volume: 20 µl
Incubation time: 20 min
Measuring range: 10 – 4000 mIU/ml

DiaSorin Liaison VZV IgM

2-step immunoluminometric sandwich assay using directly coated magnetic microparticles
Sample matrix: Serum, Plasma
Sample volume: 20 µl
Incubation time: 20 min

Product code	Product name	Method	Kit Size	Sample Type
310850	Liaison VZV IgG	2-step immunoluminometric sandwich assay	50 test kit	Serum, Plasma
310860	Liaison VZV IgM	2-step immunoluminometric sandwich assay	50 test kit	Serum, Plasma
VZVA0490	Varicella-Zoster Virus IgA	ELISA	96 wells	Serum
VZVG0490	Varicella-Zoster Virus IgG	ELISA	96 wells	Serum
VZVM0490	Varicella-Zoster Virus IgM	ELISA	96 wells	Serum

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