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Treponema
Treponema pallidum
Syphilis is a chronic infectious disease caused by sexual or congenital transmission of the Treponema pallidum spirochete. The disease progresses through distinct stages of infection characterized by diverse clinical symptoms. The appearance of a sore or chancre at the site of infection (primary stage) is followed by a generalized skin rash (secondary stage). After a variable interval of latency the infection may progress to cardiovascular problems or neurosyphilis (tertiary stage). Serological testing is essential in the detection and control of syphilis infection.
The WHO guidelines for syphilis serological diagnosis suggest the use of two combined types of serological tests for syphilis: 1) non-Treponemal tests like the Venereal Diseases Research Laboratories test (VDRL) or Rapid Plasma Reagin (RPR) and 2) Treponemal tests like the fluorescent Treponema Antibody Absorption test (FTA-ABS) or T. pallidum hemagglutination (TPHA). New European recommendations1 extended the WHO guidelines suggesting the Treponemal antigen based enzyme immunoassays as an appropriate alternative to the use of combined VDRL/RPR and TPHA screen. An excellent solution to the screening of total antibodies is the LIAISON® Treponema Screen, a fully automated chemiluminescent based test.
DiaSorin Liaison Treponema Screen
1-step immunoluminometric sandwich assay using directly coated magnetic microparticles
Sample matrix: Serum, Plasma.
Sample volume: 70 µl.
Incubation time: 30 min
Product code
Product name
Method
Kit Size
Sample Type
310840
Liaison Treponema Screen
1-step immunoluminometric sandwich assay
200 test kit
Serum, Plasma
N0148 / N0149
ETI-Treponema PLUS
ELISA
96 wells / 480 wells
Serum, Plasma
LINKS
http://www.diasorin.com/
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