 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Toxoplasma infection can cause severe damage in cases of congenitally acquired
infection. The diagnosis of primary infection in pregnant women and the timing
of infection are of particular importance. Serology is the only method to
determine if the mother has been infected by Toxoplasma gondii. Early diagnosis
of primary infection requires a highly sensitive and quantitative assay for IgG
and IgM antibodies, to discriminate between chronic and recent infections. The
presence of Toxoplasma-specific IgM in serum is an indicators of recent
infection, but often IgM persists and may be detected for years after the
occurrence of the infection. Measurement of IgG avidity may improve the accuracy
of the serological diagnosis dating the infection more precisely. A high Avidity
Index excludes recent Toxoplasma infection within the last four months.
|
|
|
|
|
|
|
|
Therefore the detection of a high IgG Avidity Index duringthe first trimester
excludes an acute infection during pregnancy for many women who, otherwise, on
the basis of a positive specific IgG and IgM result, would have been identified
as having a recent infection. |
|
|
|
|
|
|
|
DiaSorin Liaison Toxo IgG II |
|
|
|
- 2-step immunoluminometric sandwich assay using directly coated magnetic
microparticles
- Sample matrix: Serum, plasma
- Incubation time: 20 min
|
|
|
|
DiaSorin Liaison Toxo IgM |
|
|
|
- 2-step immunoluminometric sandwich assay using directly coated magnetic
microparticles
- Sample matrix: Serum, plasma
- Incubation time: 20 min
|
|
|
|
Diasorin Liaison TOXO IgG Avidity II |
|
|
|
- 3-step immunoluminometric sandwich assay using directly coated magnetic
microparticles
- Sample matrix: Serum, plasma
- Incubation time: 20 min
|
|
|
|
|
|
|
|
|
Product code |
Product name |
Method |
Kit Size |
Sample Type |
|
310710 |
Liaison Toxo IgM |
2-step immunoluminometric sandwich assay |
100 test kit |
Serum, plasma |
|
310780 |
Liaison Toxo IgG II |
2-step immunoluminometric sandwich assay |
100 test kit |
Serum, plasma |
|
310790 |
Liaison Toxo IgG Avidity II |
3-step immunoluminometric sandwich assay |
25 test kit |
Serum, plasma |
|
P002034 |
ETI-TOXOK-G PLUS |
ELISA |
192 wells |
Serum, plasma |
|
P002038 |
ETI-TOXOK-M reverse PLUS |
ELISA |
96 wells |
Serum, plasma |
|
P002039 |
ETI-TOXOK-A reverse PLUS |
ELISA |
96 wells |
Serum, plasma |
|
|
|
|
|
|
|
|
|
Back To Top |
|
|
|
|
|
|
|
|
|
The Rubella test is used to confirm the presence of adequate protection against
the Rubella virus and to detect a recent or past infection. It can also be used
to identify those who have never been exposed to the virus and those who have
not been vaccinated. The IgG Rubella test is ordered on all pregnant women and
those planning to become pregnant to verify that they have a sufficient amount
(titer) of Rubella antibodies to protect them from infection. |
|
|
|
|
|
|
|
Both the IgM and IgG antibody tests may be ordered on a person, pregnant or not,
who has symptoms of a Rubella infection. They may also be ordered on a newborn
that is suspected to have become infected during pregnancy or that presents with
congenital birth defects that the doctor suspects may be due to a Rubella
infection. |
|
|
|
|
|
|
|
DiaSorin Liaison Rubella IgG |
|
|
|
- 2-step immunoluminometric sandwich assay using directly coated magnetic
microparticles
- Sample matrix: Serum, plasma
- Incubation time: 20 min
|
|
|
|
DiaSorin Liaison Rubella IgM |
|
|
|
- 2-step immunoluminometric sandwich assay using directly coated magnetic
microparticles
- Sample matrix: Serum, plasma
- Incubation time: 30 min
|
|
|
|
|
Product code |
Product name |
Method |
Kit Size |
Sample Type |
|
310720 |
Liaison Rubella IgG |
2-step immunoluminometric sandwich assay |
100 test kit |
Serum, plasma |
|
310730 |
Liaison Rubella IgM |
2-step immunoluminometric sandwich assay |
100 test kit |
Serum, plasma |
|
P002036 |
ETI-RUBEK-M reverse PLUS (Rubella) |
ELISA |
96 wells |
Serum, plasma |
|
P002037 |
ETI-RUBEK-G PLUS (Rubella) |
ELISA |
192 wells |
Serum, plasma |
|
|
|
|
|
|
|
|
Back To Top |
|
|
|
|
|
|
|
|
|
Human Cytomegalovirus (hCMV) is the most common cause of viral intrauterine
infection. Fetal damage is mostly due to maternal primary infection.
Intrauterine transmission of CMV is significantly reduced in immunoprotected
mothers compared to primary infections contracted during pregnancy (< 2% vs
40-50%, respectively). As infections are either asymptomatic or accompanied by
symptoms which are not specific for CMV, laboratory techniques are the sole
means of diagnosing acute infections. However, the establishment of primary
infection as opposed to reactivation, chronic infection, IgM persistency or
polyclonal stimulation may be difficult on the basis of current classical CMV
IgM and IgG detection. DiaSorin LIAISON® serology line has been developed to
solve diagnostic ambiguities. Sensitive and quantitative CMV IgM, with highly
specific and quantitative CMV IgG, both complemented by CMV avidity
determination in a fully automated LIAISON® assay environment, will allow the
laboratory to report clear and unequivocal results. Positive IgM and low-avidity
IgG are suggestive of primary infection, whereas high-avidity IgG indicates IgM
presence due to persistency or reactivation. In addition, to avoid
misinterpretation of positive, yet low IgM responses in primary infection, the
IgM test will point to the need of IgG avidity determination to overrule primary
infection. |
|
|
|
|
|
|
|
DiaSorin Liaison CMV IgG |
|
|
|
- 2-step immunoluminometric sandwich assay using directly coated magnetic
microparticles
- Sample matrix: Serum, plasma
- Incubation time: 20 min
|
|
|
|
DiaSorin Liaison CMV IgM |
|
|
|
- 2-step immunoluminometric sandwich assay using directly coated magnetic
microparticles
- Sample matrix: Serum, plasma
- Incubation time: 30 min
|
|
|
|
DiaSorin Liaison CMV IgG Avidity |
|
|
|
- 3-step immunoluminometric sandwich assay using directly coated magnetic
microparticles
- Sample matrix: Serum, plasma
- Incubation time: 30 min
|
|
|
|
|
|
|
|
|
Product code |
Product name |
Method |
Kit Size |
Sample Type |
|
310740 |
Liaison CMV IgG |
2-step immunoluminometric sandwich assay |
100 test kit |
Serum, plasma |
|
310750 |
Liaison CMV IgM |
2-step immunoluminometric sandwich assay |
100 test kit |
Serum, plasma |
|
310760 |
Liaison CMV IgG Avidity |
3-step immunoluminometric sandwich assay |
25 test kit |
Serum, plasma |
|
P002033 |
ETI-CYTOK-G PLUS |
ELISA |
192 wells |
Serum, plasma |
|
P002035 |
ETI-CYTOK-M revers pLUS |
ELISA |
96 wells |
Serum, plasma |
|
24300 |
CMV-vue Kit |
IFA |
8x8 wells |
Leukocyte isolate |
|
|
|
|
|
|
|
Back To Top |
|
|
|
|
|
|
|
|
|
|
Genital herpes simplex virus (HSV) infection in pregnant women is associated
with risk of viral transmission to the infant at delivery. The identification of
risk pregnancies is necessary to avoid life-threatening consequences in
newborns. Herpes simplex virus type 2 (HSV-2) is the main cause of genital
herpes. HSV-2 reactivation or primary infection during pregnancy is common, but
the risk of associated neonatal HSV-2 infection is 10 times greater for women
with primary infection in the last trimester of pregnancy. Since most
individuals infected with HSV-2 are asymptomatic, the serological evaluation of
HSV-2 infection can reduce viral transmission. However, serological diagnosis of
HSV-2 infection has been difficult, since discrimination between HSV-1 and HSV-2
specific antibodies in serum is complicated by the shared antigenicity of the
two viruses and consequently by the considerable cross-reactivity. DiaSorin
Liaison® serology line has been developed to solve such diagnostic ambiguities.
The determination of type-specific antibodies to glycoprotein G2 allows the
laboratory to establish a specific diagnosis of HSV-2 infection in a fully
automated Liaison® environment. A highly specific and sensitive screening tool
for determination of IgG antibodies to HSV-1 and HSV-2 as well as a
complementary test for detection of Immunoglobulin M have been developed to
complete the line. |
|
|
|
|
|
|
|
DiaSorin Liaison HSV-1/2 IgG |
|
|
|
- 2-step immunoluminometric sandwich assay using directly coated magnetic
microparticles
- Sample matrix: Serum, plasma
- Incubation time: 20 min
|
|
|
|
DiaSorin Liaison HSV-2 IgM |
|
|
|
- 2-step immunoluminometric sandwich assay using directly coated magnetic
microparticles
- Sample matrix: Serum, plasma
- Incubation time: 20 min
|
|
|
|
DiaSorin Liaison HSV-1/2 IgM |
|
|
|
- 2-step immunoluminometric sandwich assay using directly coated magnetic
microparticles
- Sample matrix: Serum, plasma
- Incubation time: 20 min
|
|
|
|
|
Product code |
Product name |
Method |
Kit Size |
Sample Type |
|
310800 |
Liaison HSV-1/2 IgG |
2-step immunoluminometric sandwich assay |
100 test kit |
Serum, plasma |
|
310810 |
Liaison HSV-2 IgM |
2-step immunoluminometric sandwich assay |
100 test kit |
Serum, plasma |
|
310820 |
Liaison HSV-1/2 IgM |
2-step immunoluminometric sandwich assay |
100 test kit |
Serum, plasma |
| 310830 |
Liaison HSV-1 IgG |
2-step immunoluminometric sandwich assay |
100 test kit |
Serum, plasma |
| P002023 |
ETI-HSVK-G 1/2 (HSV-1/2 IgG) |
ELISA |
96 wells |
Serum, plasma |
| P002024 |
ETI-HSVK-G 2 (HSV-2 IgG |
ELISA |
96 wells |
Serum, plasma |
| P002025 |
ETI-HSVK-M 1/2 (HSV-1/2 IgM) |
ELISA |
96 wells |
Serum, plasma |
|
|
|
|
|
|
|
|
|
|
|
Back To Top |
|
|
|
|
|
|