Client SurveyCape Town
   
      
  Hepatitis  
   
   
     
  Hepatitis A  
     
  Hepatitis A antibody is produced in response to an infection with the Hepatitis A virus or to the Hepatitis A vaccine. The test detects the presence of this antibody.  
     
  Antibodies are produced by the body to protect it self from antigens (foreign proteins). IgM (immunoglobulin M) is the first antibody produced by the body when it is exposed to a virus and is used for early detection of infection. IgM antibodies to HAV are used in a patient with evidence of acute Hepatitis, such as jaundice, dark urine, pale colored stools, fever, and loss of appetite. IgG (immunoglobulin G) antibodies develop later and remain present for many years, protecting the person against further infection by the same virus. A total antibody test (which detects both IgM and IgG antibodies) detects both current and previous infection with HAV and also will be positive after receiving the Hepatitis A vaccine.  
     
  Testing for the presence of IgM antibodies to Hepatitis A is done if you have the symptoms and/or are likely to have been exposed to the virus. If you have being considered for the HAV vaccine, a total antibody test may be ordered before you are given the vaccine to see if you need it (if the antibodies are already present, the vaccine won’t help you). Once you have completed the two doses of the vaccine, the total HAV antibody test can also be used to see if you have responded to the vaccine.  
     
  DiaSorin Liaison Anti-HAV  
 
  • 2-step immunoluminometric sandwich assay using directly coated magnetic microparticles
  • Sample matrix: Serum, Plasma
  • Incubation time: 30 min
 
  DiaSorin Liaison HAV IgM  
 
  • 2-step immunoluminometric sandwich assay using directly coated magnetic microparticles
  • Sample matrix: Serum, Plasma
  • Incubation time: 20 min
 
     
 
Product code Product name Method Kit Size Sample Type
310170 Liaison Anti-HAV 2-step immunoluminometric sandwich assay 100 test kit Serum, plasma
310180 Liaison HAV IgM 2-step immunoluminometric sandwich assay 100 test kit Serum, plasma
N0136 ETI-AB-HAVK PLUS (Anti-HAV) ELISA 96 wells Serum, plasma
N0142 ETI-HA-IGMK PLUS (IgM Anti-HAV) ELISA 96 wells Serum, Plasma
 
     
 
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  Hepatitis B  
     
  Hepatitis B antibodies are produced in response to exposure to the Hepatitis B virus (HBV). The tests detect the presence of these antibodies or parts (antigens) of the virus itself. There are several tests used to detect the presence of Hepatitis B antibodies. Antibodies are produced by the body to offer protection from antigens (foreign proteins). There are also several tests that detect the presence of viral antigens.  
     
  Anti-HBs, Anti-HBs PLUS  
  The Hepatitis B surface antibody (Anti-HBs) is the most common test. Its presence indicates previous exposure to HBV, but the virus is no longer present and the person cannot pass on the virus to others. The antibody also protects the body from future HBV infection. In addition to exposure to HBV, the antibodies can also be acquired from successful vaccination. This test is done to determine the need for vaccination (if Anti-HBs is absent), or following the completion of vaccination against the disease, or following an active infection.  
     
  DiaSorin Liaison Anti-HBs  
 
  • 2-step immunoluminometric sandwich assay using directly coated magnetic microparticles
  • Sample matrix: Serum, Plasma
  •  Incubation time: 30 min
 
  DiaSorin Liaison Anti-HBs PLUS  
 
  • 2-step immunoluminometric sandwich assay using directly coated magnetic microparticles
  • Quantitative determination of antibodies to Hepatitis B surface antigen
  • Sample matrix: Serum, Plasma
  • Incubation time: 20 min
 
 
Product code Product name Method Kit Size Sample Type
310120 Liaison Anti-HBs 2-step immunoluminometric sandwich assay 100 test kit Serum, Plasma
310190 Liaison Anti-HBs PLUS 2-step immunoluminometric sandwich assay 100 test kit Serum, Plasma
P001603 ETI-AB-AUK-3 (Anti-HBs) ELISA 96 wells Serum, Plasma
 
 
   
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  HBsAg, HBsAg Confirmatory  
     
  Hepatitis B surface antigen (HBsAg) is a protein antigen produced by HBV. This antigen is the earliest indicator of acute Hepatitis B and frequently identifies infected people before symptoms appear. HBsAg disappears from the blood during the recovery period. In some people (particularly those infected as children or those with a weak immune system, such as those with AIDS), chronic infection with HBV may occur and HBsAg remains positive.  
     
  Sometimes, HBV goes into “hiding” in the liver and other cells and does not produce new viruses that can infect others, or produces them in such low amounts that they cannot be found in the blood. People who have this form are said to be carriers. In other cases, the body continues to make viruses that can further infect the liver and can be spread to other people. In both these cases, HBsAg will be positive.  
     
  DiaSorin Liaison HBsAg  
 
  • 2-step immunoluminometric sandwich assay using directly coated magnetic microparticles
  • Sample matrix: Serum, Plasma
  • Incubation time: 30 min
 
  DiaSorin Liaison HBsAg Confirmatory  
 
  • Pretreatment of samples with Anti-HBs antibody and specimen diluent followed by 2-step assay
  • Sample matrix: Serum, Plasma
  • Sample volume: 700 µl
  • Incubation time: 1h/RT + 20 min
 
 
Product code Product name Method Kit Size Sample Type
310100 Liaison HBsAg 2-step immunoluminometric sandwich assay 100 test kit Serum, Plasma
310110 Liaison HBsAg Confirmatory Tests 2-step immunoluminometric sandwich assay 20 test kit Serum, Plasma
N0019 ETI-MAK-4 (HBsAg) ELISA 192 wells Serum, Plasma
 
     
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  HBeAg, Anti-HBe  
     
  Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into “hiding,” the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood and lead to development of antibodies against e-antigen (Anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful.  
     
  Anti-HBe is an antibody produced in response to the Hepatitis B e antigen. In those who have recovered from acute Hepatitis B infection, Anti-HBe will be present along with Anti-HBc and Anti-HBs. In those with chronic Hepatitis B, usually Anti-HBe becomes positive when the virus goes into hiding or is eliminated from the body. In strains that do not make Hbe antigen, Anti-HBe is also positive.  
     
  DiaSorin Liaison HBeAg  
 
  • 2-step immunoluminometric sandwich assay using directly coated magnetic microparticles
  • Sample matrix: Serum, Plasma
  • Incubation time: 20 min
 
  DiaSorin Liaison Anti-HBe  
 
  • 2-step immunoluminometric sandwich assay using directly coated magnetic microparticles
  • Sample matrix: Serum, Plasma
  • Incubation time: 20 min
 
 
Product code Product name Method Kit Size Sample Type
310150 Liaison HBeAg 2-step immunoluminometric sandwich assay 100 test kit Serum, Plasma
310160 Liaison Anti-HBe 2-step immunoluminometric sandwich assay 100 test kit Serum, Plasma
N0139 ETI-AB-EBK PLUS (Anti-HBe) ELISA 96 wells Serum, Plasma
N0140 ETI-EBK PLUS (HBeAg) ELISA 96 wells Serum, Plasma
 
 
   
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  Anti-HBc, HBc IgM  
     
  Anti-Hepatitis B core antigen (Anti-HBc) is an antibody to the Hepatitis B core antigen. The core antigen is found on virus particles but disappears early in the course of infection. This antibody is produced during and after an acute HBV infection and is usually found in chronic HBV carriers as well as those who have cleared the virus, and usually persists for life. Anti-HBc testing is either specific for the IgM antibody, Anti-HBc, IgM, which indicates acute infection, or measures total antibody, Anti-HBc, which indicates past infection, either acute or chronic.  
     
  HBV DNA is a more sensitive test than HBeAg for detecting viruses in the blood stream. It is usually used in conjunction with – rather than instead of – the regular serologic tests. It may be used to monitor antiviral therapy in patients with chronic HBV infections.  
     
  DiaSorin Liaison Anti-HBc  
 
  • 2-step immunoluminometric sandwich assay using directly coated magnetic microparticles
  • Sample matrix: Serum, Plasma
  • Incubation time: 20 min
 
  DiaSorin Liaison HBc IgM  
 
  • 2-step immunoluminometric sandwich assay using directly coated magnetic microparticles
  • Sample matrix: Serum, Plasma
  • Incubation time: 20 min
 
 
Product code Product name Method Kit Size Sample Type
310130 Liaison Anti-HBc 2-step immunoluminometric sandwich assay 100 test kit Serum, Plasma
310140 Liaison HBc IgM 2-step immunoluminometric sandwich assay 50 test kit Serum, Plasma
N0137 ETI-AB-COREK PLUS (Anti-HBc) ELISA 192 wells Serum, Plasma
N0138 ETI-CORE-IgMK PLUS (IgM Anti-HBc) ELISA 96 wells Serum, Plasma
 
     
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  Hepatitis D  
     
  Hepatitis B antibodies are produced in response to exposure to the Hepatitis B virus (HBV). The tests detect the presence of these antibodies or parts (antigens) of the virus itself. There are several tests used to detect the presence of Hepatitis B antibodies. Antibodies are produced by the body to offer protection from antigens (foreign proteins). There are also several tests that detect the presence of viral antigens.  
     
 
Product code Product name Method Kit Size Sample Type
P001653 ETI-DELTAK-IGMK-2 (IgM anti-HDV) ELISA 192 wells Serum, Plasma
P002097 ETI-DELTAK-2 (HDAg) ELISA 96 wells Serum, Plasma
P2808 ETI-AB-DELTAK-2 (anti-HDV) ELISA 96 wells Serum, Plasma
 
 
   
 

LINKS

http://www.diasorin.com/

 
 
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