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Client Survey Cape Town

Diabetes

Insulin
C-Peptide

Insulin

Insulin immunoassay is of help in the diagnosis of diabetes mellitus, Insulinoma, and other carbohydrate and lipid metabolism disorders. Increased Insulin levels are observed in obese subjects, in women treated with oral contraceptives, and in patients affected by Cushing's syndrome, Insulinoma, acromegaly, and hyperthyroidism. Decreased Insulin levels are found mainly in diabetes mellitus. Circulating Insulin concentrations are generally investigated by glucose tolerance test or fasting blood glucose levels. A single random blood determination, however, may not provide sufficient information due to the wide fluctuations in time response of Insulin and blood glucose levels in different individuals and clinical conditions.

DiaSorin Liaison Insulin

1-step immunoluminometric sandwich assay using directly coated magnetic microparticles
Sample matrix: Serum , EDTA-Plasma
Sample volume: 50 µl
Incubation time: 30 min
Measuring range: 0.2 - 500 µIU/ml
Detection Limit: 0.23 µIU/ml

Product code	Product name	Method	Kit Size	Sample Type
310360	Liaison Insulin	1-step immunoluminometric sandwich assay	100 test kit	Serum, EDTA-Plasma
P001739	INSI-CTK irma	IRMA Coated Tubes (RIA)	100 Tubes	Serum
P2796	INSIK-5	RIA Double Antibody	100 Tubes	Serum

C - Peptide

Determination of C-Peptide is useful in all cases in which the Insulin assay would normally be used, in which, however, the presence of circulating Insulin antibodies and exogenous Insulin therapy interfere with the Insulin immunoassay. Determination of C-Peptide is indicated:

In diabetics during Insulin treatment to determine the residual secretory function of β-cells in order to decide if a switch to other antidiabetics or a reduction of Insulin dosage is possible.
For the diagnosis of endogenous hyperInsulinism, e.g. Insulinoma, in connection with the suppression test.
For postoperative monitoring of patients with total pancreatectomy.
In patients in whom concealed injections of Insulin are suspected but cannot be proven. In such cases, Insulin levels are very high while C-Peptide values are low or undetectable.
For monitoring patients with cyclic β-cell function.
For diagnosis and monitoring of a remission phase in juvenile diabetics

DiaSorin Liaison C- Peptide

1-step immunoluminometric sandwich assay using directly coated magnetic microparticles
Sample matrix: Serum, Plasma, Urine
Sample volume: 50 µl
Incubation time: 10 min
Measuring range: 0.01 - 30 ng/ml
Detection Limit: 0.01 ng/ml

Product code	Product name	Method	Kit Size	Sample Type
316171	Liaison C-Peptide	1-step immunoluminometric sandwich assay	100 test kit	Serum, Plasma, Urine
R0052	C-PEPTIDE	IRMA Coated Tubes (RIA)	100 Tubes	Serum, Plasma, Urine

LINKS

http://www.diasorin.com/