ugg
Client SurveyCape Town
     
 
 
     Illicit Drugs of Abuse frequently asked Questions and Answers  
               
    What are the commonly known names or street names for amphetamine, methamphetamine, cocaine, opiates and cannabinoids?
   
     
    Common known names or street names for these drugs are:
     
   
Amphetamine   Speed, amp, bennies, black beauties, chalk, uppers, hi, speed balls, beans, hiballs, beenie babies, eve, uppers, dexies
Methamphetamine   Crystal, meth, ice, glass, speed, icebergs, bergs, ecstasy, MDEA, X, xtc, MDMA, adam, crank, go, love drug, tik
Cocaine   Coke, crank, snow, flake, crack, blow, rock, line, snuff, sugar, snort, stones, powder, toot, nose candy
THC   Pot, weed, herb, bud, MJ, doobie, reefer, joint, blunts, grass, rope, hemp, roach, 420, chronic, hashish, smoke, dope, dagga,  
  cannabis, zol, marijuana
Opiates (morphine)   Horsesmack, hairy hombre, H, scag, jones, fix, heroine, methadone, pinks, downers, codeine, opium
     
    How do the drugs of abuse rapid diagnostic screening test detect the drug used?
   
     
    The U-Test 5 Multi Drugs of Abuse test is based on the principle of a competitive binding immunoassay, in which a drug conjugate competes with the drug that may be present in the urine, for limited antibody binding sites.
     
    The formation of a visible colour line in the test region shows a negative result of the urine tested. The absence of a colour band on one of the test regions indicates a positive result.
     
    A faint line in the test region indicates that the drug in the urine sample tested is near the cut-off level for the test. These samples should be re-tested and confirmed with a more specific method e.g. gas chromatography.
     
    In general, what are the drug detection periods for the most abused drugs and how long after use can drug tests detect drug presence or use?
   
     
    The following chart gives approximate detection periods for each substance in urine. The detection period depends on the amount and frequency of use, metabolic rate, body weight, body fat index, age, overall health, drug tolerance and urine pH.
     
   
Substance Urine detection period
Alcohol 12-24 hours
Amphetamine 1-4 days
Cannabis (single use) 2-3 days
Cannabis (habitual use) Up to 12 weeks
Cocaine 4-5 days
Morphine 2-4 days
Heroin 2-4 days
Metamphetamine 3-5 days
     
    If a drug test is positive, can you determine how long ago the drug was taken and over what period of time?
   
     
    No. Drug of abuse testing by blood, urine, or saliva can only detect whether or not a specific drug or drug metabolite is present at the time the test is performed. While there are very broad estimates as to how long a particular drug may have been in the system, no fluid based drug test, regardless of method, is intended to include a time variable. Many factors unique to the individual being tested determine the actual half-life of the particular drug including such variables as age, weight, sex, metabolic rate, overall health, amount of drug consumed over what period of time, etc. Therefore, no conclusions can be drawn as to when a particular drug was taken or how much was consumed with any of drug of abuse test. A forensic hair core analysis for drugs can be utilized to determine historical drug use for up to 90 days.
     
    What are the effects of sample dilution or adulteration?
   
     
    The most common method of sample manipulation to avoid a positive drug screen is dilution. Other forms of sample adulteration are the in vitro addition of adulterants or additives into the specimen sample that destroy the chemical reaction properties of drug tests.
     
    What is the likelihood that the test device is defective?
   
     
    In 98% of the time, test result errors or failure to obtain test results is the result of user error. Failure to follow instructions, inadequate sampling, and device contamination, failure to use a timer or other user related factors. Follow the tests instructions completely and carefully. Unfortunately people often ignore the test instructions or cautions expecting the test device to be accurate regardless of how it is used.
     
    What are the limitations of urine drugs of abuse rapid diagnostic screening tests?
   
     
   
  • The test is a qualitative, competitive screening test. It is not designated to determine the quantitative concentration of a drug or levels of intoxication.
  • As this is a screening test, all positive results should be confirmed with a more specific method e.g. gas chromatography or gas spectrometry.
  • Adulterated urine samples may produce erroneous results. Strong oxidizing agents such as bleach can oxidize drug analytes. Dilution of the urine sample may result in concentrations falling below the test detection limits.
  • Test results can be affected by abstaining from use for a period of time before the test.
  • Urine pH impacts on the detection time.
  • It should be clearly understood that urine drug tests are not intended to determine when drugs were used, only whether the drug screened for is present at the time the test is performed. If it is desirable to screen for historical drug use, a forensic laboratory hair analysis test is available that will screen for illicit drug use for up to 90 days, dependant on hair sample length.
    What are the standard drug test sensitivity cut-off levels established by the NIDA, WHO and SAMHSA for the different drugs of abuse?
   
     
    The table below indicates the standardized threshold concentration levels established by the international regulating authorities. These levels are reviewed and updated periodically to conform to new data on drug development, technology and testing statistics. Concentration is expressed in nanograms per millilitre solution.
     
   
SYMBOL TARGET DRUG/METABOLITE CONCENTRATION
AMP    amphetamine 1000 ng/ml
BAR barbiturates 300 ng/ml
BZO benzodiazepines 300 ng/ml
COC cocaine/benzoylecgonine 300 ng/ml
MDMA ecstasy 500 ng/ml
MET methamphetamine 1000 ng/ml
MTD methadone 300 ng/ml
OPI opiates/morphine 2000 ng/ml
PCP phencyclidine 25 ng/ml
PPX propoxyphene 300 ng/ml
TCA tricyclic antidepressants 30 ng/ml
THC marijuana/cannabis 50 ng/ml
    Back To Top    
    How long can the urine specimen be stored before testing?
   
    Specimens can be stored in a refrigerator at 2 to 8° C for up to two (2) days (48 hours) or frozen, before testing. However, it is strongly recommend that the sample is tested as soon as possible after collection.
     
    What is an opiate and what are the effects of this drug on the human body?
   
     
    MOP or Opiates are any of the addictive narcotic drugs derived from the resin of the poppy plant. Opiates are analgesics (pain relievers) which work by depressing the central nervous system. They can also depress the respiratory system. Doctors often prescribe them for severe or chronic pain. Opiates are very addictive, both physically and psychologically. Use for only a short time normally results in addiction. Some commonly used opiates are: Codeine, Heroin, Methadone, Morphine and Opium. Opiates are commonly referred to as "downers". Opiates can appear in many forms: white powder or crystals; small white, yellow or orange pills; large colourful capsules; clear liquid and dark brown, sticky bars or balls. Heroin accounts for the majority of illicit opiate abuse. Some physical indications of opiate use include: extreme loss of appetite and weight, needle tracks or punctures, black and blue marks from "skin popping", scars along veins, cramps, nausea, vomiting, excessive scratching and complaint of itching, excessive sweating, constipation, raw, red nostrils from snorting, runny nose, pin-point pupils and watery eyes, reduced vision, drowsiness, euphoria, trance-like states, excessive thirst, tremors, twitching, unkempt appearance, strong body odour, irritability, chills; slight hallucinations and lethargy. Opiates reduce attention span, sensory and motor abilities, produce irrational behaviour, depression, paranoia, and other psychological abnormalities. Morphine is excreted in the urine primarily as morphine-3-glucuronide while smaller amounts are excreted as unchanged free morphine and other metabolites. It is also the major metabolic product of codeine and heroin. Morphine is detectable in the urine after 2 hours for 2-3 days after an opiate dose.
     
    Common known names or street names for these drugs are:
    Horsesmack, hairy hombre, H, scag, jones, fix, heroine, methadone, pinks, downers, codeine, opium.
     
    What is the difference between heroin and morphine?
   
     
    Heroin, morphine and codeine are opiates derived from the resin of the opium poppy. Heroin is quickly metabolized to morphine. The body also changes codeine (used in some cold medicines) to morphine. Therefore, the presence of morphine in the urine indicates heroin, morphine, and/or codeine use.
                   
 

Back To Top    

 
    Can a positive test for opiates be obtained from consuming food products that contain poppy seed?
   
                   
    If the sensitivity cut-off level of the test is the revised standard of 2000 ng/ml OPI, this is not possible. Sensitivity standards were raised in the year 2000 from 300 ng/ml to 2000 ng/ml OPI to eliminate the possibility of false positive results that were possible from consumption of large quantities of poppy seeds or poppy seed paste at the lower sensitivity level.
     
    What is amphetamine and what are the effects of this drug on the human body?
   
     
    AMP is a class of potent sympathomimetic agents with therapeutic applications. These drugs are chemically related to the human body's natural catecholamine, epinephrine and nor-epinephrine. Amphetamines are central nervous stimulants whose effects include alertness, wakefulness, increased energy, reduced hunger and an overall feeling of well being. Large doses and long term usage can result in higher tolerance levels and dependence. More acute responses produce anxiety, paranoia, hallucinations, and psychotic behaviour. The effects of amphetamines generally last 2-4 hours following use and are detectable after 2-7 hours in the urine and for 2-4 days after use. About 30% of amphetamines are excreted in the urine in unchanged form, with the remainder excreted as hydroxylated and deaminated derivatives. The most common source for amphetamine is the prescription diet pills.
     
    Common known names or street names for these drugs are:
    Speed, amp, bennies, black beauties, chalk, uppers, hi, speed balls, beans, hiballs, beenie babies, eve, uppers, dexies.
     
    What is a methamphetamine and what are the effects of this drug on the human body?
   
     
    MET is a potent sympathomimetic agent with therapeutic applications. Methamphetamine is a stimulant drug which is quickly metabolized to amphetamine. It is used in pill or in powdered form by snorting or injecting. Crystallized methamphetamine is inhaled by smoking and is a considerably more powerful form of the drug. Some of the effects of methamphetamine use include: increased heart rate, wakefulness, physical activity and decreased appetite. Cardiovascular responses to MET include increased blood pressure and cardiac arrhythmias. More acute responses include anxiety, paranoia, hallucinations, psychotic behaviour, and eventually, depression and exhaustion. The effects of MET generally last 2-4 hours and the drug have a half-life of 9-24 hours in the body. MET is excreted in the urine primarily as amphetamine and oxidized and deaminated derivatives. However, 10-20% of MET is excreted unchanged. Thus, the presence of the parent compound in the urine indicates MET use. MET is generally detectable in the urine for 3-5 days, depending on urine pH level. Methamphetamine use can cause irreversible damage to the brain, producing strokes and convulsions, which can lead to death. Ecstasy and Tik, new trendy and popular drugs among teenagers are a refined and processed form of methamphetamine.
     
    Common known names or street names for these drugs are:
    Crystal, meth, ice, glass, speed, icebergs, bergs, ecstasy, MDEA, X, xtc, MDMA, adam, crank, go, love drug, tik.
     
    What is the difference between Methamphetamine and Amphetamine?
   
    Both amphetamine and methamphetamine are potent symphathominetic agents. Methamphetamine is the parent drug. It metabolizes (or changes) into amphetamine in the body. Methamphetamine and/or amphetamine are excreted in the urine. A positive result for Amphetamine can also be interpreted as a positive test for methamphetamine.
     
    What is Ecstasy?
   
     
    Ecstasy (MDMA) is a popular recreational drug. Ecstasy is a refined processed form of amphetamine with a chemical structure closely resembling that of methamphetamine. Any test with a target screen for methamphetamine should detect Ecstasy.
     
    What is Cocaine and what are the effects of this drug on the human body?
   
     
    COC, Cocaine or Coke is made from coca leaves. It is a potent central nervous system stimulant and a local an anaesthetic. Its effects include alertness, wakefulness, increased energy and an overall feeling of euphoria. These psychological effects are accompanied by increased heart rate, dilation of the pupils, fever, tremors and sweating. Cocaine may be smoked, inhaled ("snorted") or injected. Cocaine can be a very addictive drug. It is excreted in the urine primarily as benzoylecgonine shortly after use. Benzoylecgonine has a longer biological half-life (5-8 hours) than cocaine (0.5-1.5 hours) and can generally be detected after 1-4 hours for 2-3 days after cocaine use or exposure.
     
    Common known names or street names for these drugs are:
    Coke, crank, snow, flake, crack, blow, rock, line, snuff, sugar, snort, stones, powder, toot, nose candy.
     
    How long after Cocaine use can it be detected in the urine?
   
     
    Cocaine is excreted in the urine primarily as benzoylecgonine shortly after use. Benzoylecgonine can generally be detected for 24 to 60 hours after cocaine use or exposure. Exact clearance rate times can't be determined as the metabolic rate is individualized depending on weight and other factors.
     
    What is Cannabinoids and what are the effects of these drugs on the human body?
   
     
    THC (9-tetrahydrocannabinol) is the primary active ingredient in Cannabinoids (Cannabis/ Dagga/ Marijuana). It is a hallucinogen, commonly ingested by smoking, but it may also be eaten. Cannabinoids may impair short –term memory, learning and coordination abilities. It is most commonly the drug of choice among teenagers and young adults and the most common recreational drug of abuse. The hallucinogenic effect of Cannabinoids can lead to irrational behaviour, disorientation, confusion, anxiety and paranoia. The peak effect of smoking THC occurs within 20-30 minutes and the duration is 90-120 minutes after one cigarette. Elevated levels of urinary metabolites are found within 6-18 hours after exposure and remain detectable for 3-10 days after smoking. In chronic use it remains detectable for up to 30 days after smoking the main metabolite excreted in the urine is 11-nor- 9-tetrahydrocannabinol-9-carboxylic acid.
     
    Common known names or street names for these drugs are:
    Pot, weed, herb, bud, MJ, doobie, reefer, joint, blunts, grass, rope, hemp, roach, 420, chronic, hashish, smoke, dope, dagga, cannabis, zol, marijuana.
     
    What does THC mean?
   
     
    THC is an abbreviation for 11-nor-delta9 Tetrahydrocannibinol-9-carboxylic acid, the primary metabolite of Cannabis or Marijuana. Marijuana is a hallucinogenic agent derived from the leaves, flowers or seeds of the hemp plant. In general, the production and "curing" of the marijuana plant into its useable form closely resembles that of tobacco. Marijuana is almost always smoked and inhaled into the lungs where it is quickly metabolized (or changed) by the body into 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid which is excreted in the urine.
     
    Can I test positive for THC from exposure to "second hand smoke"?
   
     
    No. Urine concentrations of THC above the cut-off sensitivity level of the test, or a positive result, are not possible by exposure to second hand smoke.
   
Client SurveyCape Town
          Back To Top      
 
Copyright © Humor Diagnostica